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PXS-5505

Hi

I was wondering if there has been any recent updates on PXS-5505 and if it is available yet.

Also is there any evidence that Relaxin2 has been used to treat arthrofibrosis.

thanks

Daryl

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Hi Daryl,

Unfortunately, we're still looking for funding to run a clinical trial on PXS-5505, so it's still some years away.


Yes, there are studies using animal models of arthrofibrosis and cell cultures that show Relaxin 2 is effective and safe, but so far as I know it doesn't yet have regulatory approval for sale. This paper is freely available if you want to read more: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9948766/

The researchers used an encapsulated version so that multiple injections into the joint weren't needed.


Let me know if you have further questions.


All the best,

Kayley


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