Drivers
Arthrofibrosis is caused by the interactions of thousands of different genes after an initiating event that causes cell death. Whether any particular individual develops arthrofibrosis (or another fibrotic condition) depends on a large number of factors. Some of these are not under our control – these include injury, infection and our genetic predisposition. Other factors are can be altered. For example, aggressive exercise, poor diet, smoking and (physical) stress.
Primary Drivers
Inflammation
Osteoarthritis, blood clotting disorder, MBL deficiency, genetic predisposition, high sugar - low fibre diet, obesity, diabetes, other conditions.
Infection
Joint infection, gum infection (P. gingivalis), respiratory infection, other infection.
Insult
Surgery - especially where the bone is cut, injury, wear and tear, unknown cause.
Secondary Drivers
Aggressive Exercise
Aggressive exercise of the affected limb. Exercise tolerance varies greatly between individuals.
Hypoxia
Lorem ipsum dolor sit amet, consectetur adipiscing elit.
Lack of Essential
Nutrients
Inflamed stomach/gut, poor diet, lack of sunlight (vit. D), other conditions.
Stress
Psychological and physical stress
Autoimmune Disorder
Rheumatoid arthritis, Ankylosing spondylitis, Lupus (SLE), Grave's disease, Mixed connective tissue disease, Other.
Lack of Quality Sleep
Sleep apnoea, poor sleep hygiene, insomnia, pain, stress, other conditions
Legal Disclaimer
The materials presented in this site are provided voluntarily as a public service. It is of a general nature, based on the scientific literature. The information and advice provided is made available in good faith but is provided solely on the basis that readers will be responsible for managing their own assessment of the matters discussed herein and that they should verify all relevant representations, statements and information. Please consult your doctor.