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Arthrofibrosis is caused by the interactions of thousands of different genes after an initiating event that causes cell death. Whether any particular individual develops arthrofibrosis (or another fibrotic condition) depends on a large number of factors. Some of these are not under our control – these include injury, infection and our genetic predisposition. Other factors are can be altered. For example, aggressive exercise, poor diet, smoking and (physical) stress.

Primary Drivers


Osteoarthritis, blood clotting disorder, MBL deficiency, genetic predisposition, high sugar - low fibre diet, obesity, diabetes, other conditions.



Joint infection, gum infection (P. gingivalis), respiratory infection, other infection.



Surgery - especially where the bone is cut, injury, wear and tear, unknown cause.

Surgical Scissors

Secondary Drivers

Aggressive Exercise

Aggressive exercise of the affected limb. Exercise tolerance varies greatly between individuals.

Joint pain, Arthritis and tendon problems. a man touching nee at pain point.jpg


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Lack of Essential


Inflamed stomach/gut, poor diet, lack of sunlight (vit. D), other conditions.

Vegetables in Paper Bags


Psychological and physical stress

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Autoimmune Disorder

Rheumatoid arthritis, Ankylosing spondylitis, Lupus (SLE), Grave's disease, Mixed connective tissue disease, Other.

DNA Strand

Lack of Quality Sleep

Sleep apnoea, poor sleep hygiene, insomnia, pain, stress, other conditions

Sleeping in Green Sheets

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The materials presented in this site are provided voluntarily as a public service. It is of a general nature, based on the scientific literature. The information and advice provided is made available in good faith but is provided solely on the basis that readers will be responsible for managing their own assessment of the matters discussed herein and that they should verify all relevant representations, statements and information. Please consult your doctor.

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