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New research shows that the resolution of pain is an active process dependent on particular immune cells called monocytes. One particular type of monocyte produces a signaling molecule called IL10, which binds to nerve cells to turn off pain. More IL-10 is produced in men than in women.

Sim et al (2026 Neuroimmunology) say "In humans, pain resolved faster in men than in women after traumatic injury and was associated with higher circulating monocytes

and IL-10 levels in men". And "The slower resolution of pain in women increases their risk

of transitioning to chronic pain".

See https://medicalxpress.com/news/2026-02-chronic-pain-longer-women-immune.html?utm_source=nwletter&utm_medium=email&utm_campaign=daily-nwletter for the story.

Kayley

Orthopaedic surgeon explains on his YouTube channel The Surgeon Unmasked why surgery to fix a meniscus tear is usually not a good idea. See https://www.youtube.com/watch?v=4Ffr2AD9tHM

A Guardian investigation has found “people were being put at risk of harm by false and misleading health information” produced by AI Overviews. For the full story see https://www.theguardian.com/technology/ng-interactive/2026/jan/24/how-the-confident-authority-of-google-ai-overviews-is-putting-public-health-at-risk

A new paper has reported that people with diabetes who took semaglutide (brand names Ozempic and Wagovy) before a knee replacement had significantly better post-op recovery, and complications such as bleeding, inflammation and infection were reduced. Substantial reductions in post-op complications were observed when semaglutide was taken for three months before surgery. The research was published by Yale orthopedic surgeons in the Journal of Arthroplasty. See https://medicalxpress.com/news/2026-01-semaglutide-knee-patients-diabetes.html?utm_source=nwletter&utm_medium=email&utm_campaign=daily-nwletter to read the media story.

Kayley

This in-depth interview with experienced arthrofibrosis surgeon Dr. Marco Valoroso has been published as a podcast on Spotify. Please visit https://open.spotify.com/episode/1x2EjrBf8L7TRlf5Zy4hQ2?si=aGPVEKc1T5enCpqS5229dQ

or watch the video on YouTube at https://www.youtube.com/watch?v=GAha434oQyQ

This interview explores the diagnosis and treatment strategies for arthrofibrosis after total knee replacement (TKR). Key advice is provided for patients and clinicians managing this challenging condition. Join Manon Raap from the IAA as she sits down with Dr. Marco Valoroso, Head of Knee Surgery at EOC Hospitals in Lugano, Switzerland, member of EUKAF center, and a leading surgeon in knee arthrofibrosis.

Entering the end of my firat year living with AF and the first holiday season. Lots of events with acquaintances or people I don't really know at all. I'm sure I'm not the only one. So how do you deal with the intrusive questions and comments?

I can't wear heels anymore. If I stand too long, I'm stiff and in pain, if I sit too long I'm stiff and in pain. My limping gait is fairly obvious. Prompting many of the inquiries.

I have the basic answer for anybody who asks (an autoimmune reaction to my knee replacement surgery, where my body doesn't know to stop making scar tissue). And last week at a party, I basically told the person who tried to equate my AF with having received the covid shot to walk away from me immediately!

But I am so tired of people either telling me they are…

Dear IAA members,

Wishing you a lovely Christmas and a healthy and happy New Year.

All the best,

Kayley

Hi,to make a 2 j and 7 months story short,i had an ACL en meniscus surgery in 2023,i had 3 surgery ‘s to remove a lot off scartissue,and it came back😌

Now i am waiting for a date to have surgery ,in Austria in Hochrum

But i have a question,i ead a lot about not using a shaver ,also about ‘ releasing’ the scartissue,my last surgery was a capsel releas’,all around the knee,is this the same ?

Thank you😘

This little walking bike has brought me (and my partner) 😀a lot of joy! Due to minimal flexion (30) walking outside, espacially on uneven surfaces, is a challenge. I use one crutch for shorter distances. But for longer walks, especially in european cities with historical pavements, my partner was always my support. Also he had to adapt to my low speed. Now he has to run after me as I speed over all the little bumps on the road, en we can cover more kilometers. We already crossed through Amsterdam, Perugia, Palermo, Edinburgh, Glasgow. We even use it in nature, when there are more or less straight paths. Hills are a problem, but we don't have a lot of them in Holland. It is allowed inside restaurants and shops, and also to take on a plane, although most airport officials are in full confusion when we present it, and the…